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4-(TRIFLUOROMETHYL)BENZYL BROMIDE
- Chemical Name: 4-(TRIFLUOROMETHYL)BENZYL BROMIDE
- CAS: 402-49-3
- Purity: 99%
Quality products?make an important contribution to long-term revenue and profitability. Good factory supply good 4-(TRIFLUOROMETHYL)BENZYL BROMIDE 402-49-3
1.What is the 4-(TRIFLUOROMETHYL)BENZYL BROMIDE ?
4-(Trifluoromethyl)benzyl bromide can be used to produce p-trifluoromethylbenzyl phenyl sulfide. It is used in medicine.
-
-
774197-61-4
3-(p-trifluoromethylbenzyloxy)-3-bromoaziridine
-
-
6140-17-6
4-methylbenzotrifluoride
-
-
402-49-3
4-bromomethyltrifluoromethylbenzene
| Conditions | Yield |
|---|---|
|
With
cyclohexa-1,4-diene;
In
chloroform;
at 20 ℃;
for 1h;
Further Variations:;
Reagents;
Product distribution;
UV-irradiation;
|
85 % Spectr.
15 % Spectr. |
-
-
349-95-1
4-(trifluoromethyl)benzylic alcohol
-
-
402-49-3
4-bromomethyltrifluoromethylbenzene
| Conditions | Yield |
|---|---|
|
With
1H-imidazole; bromine; triphenylphosphine;
In
dichloromethane;
at 0 - 22 ℃;
Inert atmosphere;
|
86%
|
|
With
tetra-(n-butyl)ammonium iodide; ethylene dibromide; triphenylphosphine;
at 60 ℃;
for 2h;
Sealed tube;
Inert atmosphere;
|
63%
|
|
With
hydrogen bromide;
In
benzene;
Heating;
|
37%
|
|
With
hydrogen bromide;
|
|
|
With
hydrogen bromide;
|
|
|
With
sulfuric acid; hydrogen bromide;
|
|
|
(bromination);
|
|
|
With
hydrogen bromide;
|
|
|
With
hydrogen bromide;
for 12h;
Heating;
|
|
|
With
hydrogen bromide;
In
chloroform;
Ambient temperature;
|
|
|
With
phosphorus tribromide;
In
diethyl ether;
at -40 ℃;
|
|
|
With
phosphorus tribromide;
In
diethyl ether;
at 0 ℃;
for 0.5h;
|
|
|
In
water; hydrogen bromide;
|
|
|
With
phosphorus tribromide;
In
dichloromethane;
at 0 ℃;
for 0.5h;
|
|
|
With
phosphorus tribromide;
In
diethyl ether;
at 0 ℃;
for 0.5h;
|
|
|
With
phosphorus tribromide;
In
diethyl ether;
at 0 ℃;
for 0.5h;
|
2.What is the CAS number for 4-(TRIFLUOROMETHYL)BENZYL BROMIDE ?
The CAS number of 4-(TRIFLUOROMETHYL)BENZYL BROMIDE is 402-49-3.
More information of 4-(TRIFLUOROMETHYL)BENZYL BROMIDE 402-49-3 are:
|
CAS?Number |
402-49-3 |
|
Density |
1.568 g/cm3 |
|
Melting Point |
29-33 °C(lit.) |
|
Boiling Point |
202.9 °C at 760 mmHg |
|
Flash Point |
88.9 °C |
|
Vapor Pressure |
4.85mmHg at 25°C |
|
Refractive Index |
n20/D 1.484(lit.) |
|
HS CODE |
29039990 |
|
PSA |
0.00000 |
|
LogP |
3.60030 |
3.What are another words for 4-(TRIFLUOROMETHYL)BENZYL BROMIDE ?
Synonyms?for?4-(TRIFLUOROMETHYL)BENZYL BROMIDE 402-49-3:p-Xylene,a'-bromo-a,a,a-trifluoro- (7CI,8CI);1-(Bromomethyl)-4-(trifluoromethyl)benzene;1-Trifluoromethyl-4-(bromomethyl)benzene;4-(Trifluoromethyl)benzyl bromide;p-(Trifluoromethyl)benzyl bromide;a'-Bromo-a,a,a-trifluoro-p-xylene;
4.What is the molecular formula of 4-(TRIFLUOROMETHYL)BENZYL BROMIDE?
The chemical formula of ?4-(TRIFLUOROMETHYL)BENZYL BROMIDE is?C8H6BrF3 which containing 8 Carbon atoms,6 Hydrogen atoms,1 Bromine atoms and 3 Fluorine atoms,and the molecular weight of??4-(TRIFLUOROMETHYL)BENZYL BROMIDE?is 239.035.
5.What is 4-(TRIFLUOROMETHYL)BENZYL BROMIDE (402-49-3) used for?
4-(Trifluoromethyl)benzyl Bromide is an organic compound characterized by the presence of a trifluoromethyl group attached to a benzyl bromide moiety. It is a valuable building block in the synthesis of various pharmaceutical compounds due to its unique structural features and reactivity.
InChI:InChI=1/C9H7F3/c1-2-7-3-5-8(6-4-7)9(10,11)12/h2-6H,1H2
Relevant articles related to 4-(TRIFLUOROMETHYL)BENZYL BROMIDE:
|
Article |
Source |
|
Aryl Sulfonium Salts for Site-Selective Late-Stage Trifluoromethylation |
Ye, Fei,Berger, Florian,Jia, Hao,Ford, Joseph,Wortman, Alan,B?rgel, Jonas,Genicot, Christophe,Ritter, Tobias , p. 14615 - 14619 (2019/09/17) |
|
Synthesis and biological evaluation of curcumin inspired indole analogues as tubulin polymerization inhibitors |
Sri Ramya,Angapelly, Srinivas,Guntuku, Lalita,Singh Digwal, Chander,Nagendra Babu, Bathini,Naidu,Kamal, Ahmed , p. 100 - 114 (2016/12/30) |
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