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4,4'-pentamethylenedioxydibenzonitrile
- Chemical Name: 4,4'-pentamethylenedioxydibenzonitrile
- CAS: 7467-71-2
- Purity: 99%
Cost-effective and customizable 4,4'-pentamethylenedioxydibenzonitrile 7467-71-2 for sale
- Molecular Formula:C19H18 N2 O2
- Molecular Weight:306.364
- Boiling Point:515.4°Cat760mmHg
- Flash Point:199.7°C
- Density:1.16g/cm3
7467-71-2 Relevant articles
Small Molecule Inhibitors of Ca2+-S100B Reveal Two Protein Conformations
Cavalier, Michael C.,Ansari, Mohd. Imran,Pierce, Adam D.,Wilder, Paul T.,McKnight, Laura E.,Raman, E. Prabhu,Neau, David B.,Bezawada, Padmavani,Alasady, Milad J.,Charpentier, Thomas H.,Varney, Kristen M.,Toth, Eric A.,MacKerell, Alexander D.,Coop, Andrew,Weber, David J.
, p. 592 - 608 (2016/02/09)
The drug pentamidine inhibits calcium-de...
Biological Efficacy and Toxicity of Diamidines in Myotonic Dystrophy Type 1 Models
Siboni, Ruth B.,Bodner, Micah J.,Khalifa, Muhammad M.,Docter, Aaron G.,Choi, Jessica Y.,Nakamori, Masayuki,Haley, Michael M.,Berglund, J. Andrew
, p. 5770 - 5780 (2015/08/24)
Myotonic dystrophy type 1 (DM1) is a dis...
ARYL DIAMIDINES AND PRODRUGS THEREOF FOR TREATING MYOTONIC DYSTROPHY
-
Paragraph 0115, (2013/11/05)
Disclosed herein are compounds (for exam...
Structure-activity study of pentamidine analogues as antiprotozoal agents
Bakunova, Svetlana M.,Bakunov, Stanislav A.,Patrick, Donald A.,Kumar, E. V. K. Suresh,Ohemeng, Kwasi A.,Bridges, Arlene S.,Wenzler, Tanja,Barszcz, Todd,Jones, Susan Kilgore,Werbovetz, Karl A.,Brun, Reto,Tidwell, Richard R.
scheme or table, p. 2016 - 2035 (2009/12/31)
Diamidine 1 (pentamidine) and 65 analogu...
7467-71-2 Process route
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-
111-24-0
1,5-dibromo-pentane
-
-
767-00-0
4-cyanophenol
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-
7467-71-2
4,4′-(pentane-1,5-diylbis(oxy))dibenzonitrile
| Conditions | Yield |
|---|---|
|
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 1h;
|
95.7% |
|
With
potassium carbonate;
In
1,4-dioxane;
for 120h;
Reflux;
|
75% |
|
With
sodium;
In
ethanol;
|
74% |
|
With
sodium ethanolate;
for 48h;
Heating;
|
|
|
With
sodium hydroxide;
Yield given. Multistep reaction;
1.) C2H5OH, reflux, 1 h, 2.) C2H5OH, reflux, 3 h;
|
|
|
|
|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
Reflux;
|
|
|
With
potassium carbonate;
In
acetonitrile;
Reflux;
|
|
|
With
caesium carbonate;
In
acetone;
for 14h;
Reflux;
Inert atmosphere;
|
-
-
13031-41-9
4-cyanophenyl acetate
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-
7467-71-2
4,4′-(pentane-1,5-diylbis(oxy))dibenzonitrile
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: 88 percent / 4percent KOH / ethanol / 0.33 h / Heating
2: 1.) aq. NaOH / 1.) C2H5OH, reflux, 1 h, 2.) C2H5OH, reflux, 3 h
With
potassium hydroxide; sodium hydroxide;
In
ethanol;
|
7467-71-2 Upstream products
-
111-24-0
1,5-dibromo-pentane
-
3328-57-2
sodium 4-cyanophenolate
-
767-00-0
4-cyanophenol
-
13031-41-9
4-cyanophenyl acetate
7467-71-2 Downstream products
-
1252-44-4
4,4'-pentanediyldioxy-bis-benzimidic acid diethyl ester
-
224054-40-4
4,4'-pentanediyldioxy-bis-benzylamine
-
84223-65-4
2,2'-
di-2-imidazolin-dihydrochlorid -
100-33-4
pentamidine






