Pharmaceutical

Bufexamac

  • Chemical Name: Bufexamac
  • CAS: 2438-72-4
  • Purity: 99%
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1.What is the Bufexamac ?

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ChEBI: A hydroxamic acid derived from phenylacetamide in which the benzene moiety is substituted at C-4 by a butoxy group. It has anti-inflammatory, analgesic, and antipyretic properties.

Bufexamac is a hydroxamic acid derived from phenylacetamide, with the benzene moiety substituted at C-4 by a butoxy group. It is a non-steroidal anti-inflammatory drug (NSAID) known for its anti-inflammatory, analgesic, and antipyretic properties. Bufexamac is used both topically and rectally, and is particularly effective as a specific inhibitor of class IIB histone deacetylases (HDAC6 and HDAC10). It is available under various brand names, such as Anderm, Paraderm, Parfenac, Bufemac, and Bufexine ratiopharm.

2.What is the CAS number for Bufexamac ?

The CAS number of Bufexamac is 2438-72-4.

3.What are another words for Bufexamac ?

Synonyms?for?Bufexamac 2438-72-4:4-Butoxy-N-hydroxybenzeneacetamide;p-Butoxyphenylacetohydroxamic acid;Benzeneacetamide, 4-butoxy-N-hydroxy- (9CI);

4.What is Bufexamac (2438-72-4) used for?

Bufexamac is a non-steroidal topical medication used for treatment of a variety of problems in which the skin is inflamed. These vary widely from insect bites to bums, plant stings and a wide variety of medical conditions induding psoriasis, hemorrhoidal symptoms, eczema and inflammation of the skin following radiotherapy. In this last case, it can be used before radiotherapy to help prevent inflammation of the skin caused by radiation therapy.

InChI:InChI=1/C12H17NO3/c1-2-3-8-16-11-6-4-10(5-7-11)9-12(14)13-15/h4-7,15H,2-3,8-9H2,1H3,(H,13,14)

Relevant articles related to Bufexamac:

Article

Source

Hydroxamic acid inhibitors of 5-lipoxygenase: Quantitative structure-activity relationships

Summers,Kim,Mazdiyasni,Holms,Ratajczyk,Stewart,Dyer,Carter

, p. 992 - 998 (2007/10/02)

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